Forskning om IBS

Forskning om IBS har utvecklats mycket och kostbehandlingen FODMAP är ett resultat av detta. Det har forskats fram på Monash University i Australien. FODMAP används idag som förstahandsbehandling vid IBS i de flesta länder i världen och får endast utföras av leg dietister. Belly Balance behandling baseras på FODMAP och är framtagen av och kvalitetssäkrad av leg dietist Sofia Antonsson.

Det finns många studier på IBS och FODMAP och forskning pågår på flera ställen i världen, bl a på Kings College i London. Här har vi samlat ett urval av de studier som publicerats.

Forskning om IBS – länkar

The Low FODMAP Diet Reduces Symptoms in Irritable Bowel Syndrome Compared With Placebo Diet and the Microbiota Alterations May Be Prevented by Probiotic Co-Administration: A 2×2 Factorial Randomized Controlled Trial

Heidi M. Staudacher^1,4, Miranda Lomer^1,4, Petra Louis⁵, Freda Farquharson⁵, James O. Lindsay², Peter M. Irving^1,3, Kevin Whelan¹. School of Medicine, Diabetes and Nutritional Sciences Division, King’s College London, London, United Kingdom

Clinical trial demonstrates success of low FODMAP diet. In a first of its kind study in the US, those with IBS overcame symptoms with diet changes compared to control.

The evidence base for efficacy of the low FODMAP diet in irritable bowel syndrome: is it ready for prime time as a first-line therapy?

Dietary Treatment of Endometriosis-related Irritable Bowel Syndrom

Low FODMAP diet – Efficacy in managing abdominal symptoms in patients with endometriosis. Moore, J. et al. Journal of Nutrition & Intermediary Metabolism, Volume 1, 14.

Fermentable Carbohydrate Restriction (Low FODMAP Diet) in Clinical Practice Improves Functional Gastrointestinal Symptoms in Patients with Inflammatory Bowel Disease.

Prince AC, Myers CE, Joyce T, Irving P, Lomer M, Whelan K. Inflammatory bowel disease 2016 May;22(5):1129-36.

Effect of Gender on Prevalence of Irritable Bowel Syndrome in the Community: Systematic Review and Meta-Analysis.

Lovell RM, Ford AC. Am J Gastroenterol. 2012 May 22. doi: 10.1038/ajg.2012.131. [Epub ahead of print] PMID: 22613905

Comparison of symptom response following advice for a diet low in fermentable carbohydrates (FODMAPs) versus standard dietary advice in patients with irritable bowel syndrome

Staudacher HM, Whelan K, Irving PM, Lomer MC. J Hum Nutr Diet. 2011 Oct;24(5):487-95. doi: 10.1111/j.1365-277X.2011.01162.x. Epub 2011 May 25. PubMed [citation]PMID:21615553

Food intolerance in functional bowel disorders.

Gibson PR. J Gastroenterol Hepatol. 2011 Apr;26 Suppl 3:128-31. doi: 10.1111/j.1440-1746.2011.06650.x. Review.PubMed [citation]PMID:21443725

Food: The Forgotten Factor in the Irritable Bowel Syndrome

Shanti Eswaran, MD, Jan Tack, MD, PhD, William D. Chey, MD, AGAF. Gastroenterology Clinics of North America. Volume 40, Issue 1 , Pages 141-162, March 2011

Diarrhoea during enteral nutrition is predicted by the poorly absorbed short-chain carbohydrate (FODMAP) content of the formula.

Halmos EP, Muir JG, Barrett JS, Deng M, Shepherd SJ, Gibson PR. Aliment Pharmacol Ther. 2010 Oct;32(7):925-33. doi: 10.1111/j.1365-2036.2010.04416.x. PubMed [citation]PMID:20670219

Manipulation of dietary short chain carbohydrates alters the pattern of gas production and genesis of symptoms in irritable bowel syndrome.

Ong DK, Mitchell SB, Barrett JS, Shepherd SJ, Irving PM, Biesiekierski JR, Smith S, Gibson PR, Muir JG. J Gastroenterol Hepatol. 2010 Aug;25(8):1366-73. PubMed [citation]PMID:20659225

Evidence-based dietary management of functional gastrointestinal symptoms: The FODMAP approach.

Gibson PR, Shepherd SJ. J Gastroenterol Hepatol. 2010 Feb;25(2):252-8. Review. PubMed [citation]PMID:20136989

Dietary poorly absorbed, short-chain carbohydrates increase delivery of water and fermentable substrates to the proximal colon.

Barrett JS, Gearry RB, Muir JG, Irving PM, Rose R, Rosella O, Haines ML, Shepherd SJ, Gibson PR. Aliment Pharmacol Ther. 2010 Apr;31(8):874-82. Epub 2010 Jan 22. PubMed [citation]PMID:20102355

The FODMAP diet for irritable bowel syndrome: food fad or roadmap to a new treatment paradigm?

Rangnekar AS, Chey WD. Gastroenterology. 2009 Jul;137(1):383-6. Epub 2009 May 29. No abstract available. PubMed [citation]PMID:19482108

Reduction of dietary poorly absorbed short-chain carbohydrates (FODMAPs) improves abdominal symptoms in patients with inflammatory bowel disease-a pilot study.

Gearry RB, Irving PM, Barrett JS, Nathan DM, Shepherd SJ, Gibson PR. J Crohns Colitis. 2009 Feb;3(1):8-14. Epub 2008 Dec 6. PubMed [citation]PMID:21172242

Comparison of the prevalence of fructose and lactose malabsorption across chronic intestinal disorders.

Barrett JS, Irving PM, Shepherd SJ, Muir JG, Gibson PR. Aliment Pharmacol Ther. 2009 Jul 1;30(2):165-74. Epub 2009 Apr 15. PubMed [citation]PMID:19392860

Dietary triggers of abdominal symptoms in patients with irritable bowel syndrome: randomized placebo-controlled evidence.

Shepherd SJ, Parker FC, Muir JG, Gibson PR. Clin Gastroenterol Hepatol. 2008 Jul;6(7):765-71. Epub 2008 May 5. PubMed [citation]PMID:18456565